Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease that primarily affects women. It is characterized by the destruction of the bile ducts in the liver, leading to a build-up of toxic substances and damage to liver cells. Symptoms of PBC can include fatigue, itching, jaundice, and abdominal pain. Research in the field of PBC focuses on understanding the underlying causes of the disease, developing better diagnostic tools, and exploring new treatments to improve patient outcomes. This research often involves studying the immune system's role in attacking the bile ducts, identifying genetic factors that increase the risk of PBC, and testing new medications that may slow the progression of the disease. Overall, the goal of PBC research is to improve the quality of life for patients with this chronic liver condition.